Studies of hepatic excretory function. The effect of 17alpha-ethyl-19-nortestosterone on sulfobromophthalein sodium (BSP) metabolism in man.

Studies of Sulfobromophthalein Sodium (bsp) Metabolism in Man. I. in Normal Subjects and Patients with Hepatic Disease.

Studies of Sulfobromophthalein Sodium (bsp) Metabolism in Man. Ii. the Effect of Artificially Induced Fever, Norethandrolone (nilevar), and Iopanoic Acid (telapaque).

A liver enzyme that conjugates sulfobromophthalein sodium with glutathione.

In the past few years, considerable evidence has been presented indicating that sulfobromophthalein sodium (BSP) is metabolized in the liver (1-6). Recently, we have demonstrated that the major pathway of BSP metabolism in man and in the rat involves conjugation of BSP with.the tripeptide glutathione (5). Similar results have been obtained by Javitt and his associates in the dog (6). Grodsky, C...

Studies of Sulfobromophthalein Sodium (bsp) Metabolism in Man. 3. Demonstration of a Transport Maximum (tm) for Biliary Excretion of Bsp.

The effect of sodium taurocholate on the hepatic metabolism of sulfobromophthalein sodium (BSP). The role of bile flow.

The influence of bile salts on the hepatic metabolism of sulfobromophthalein sodium (BSP) was studied in the perfused rat liver. During sodium taurocholate infusions, hepatic uptake of BSP from plasma was increased and appeared to be related to an enhanced transit of BSP from liver into bile. BSP-glutathione conjugation was not affected by the bile salt infusions, although bile salts inhibited ...